The National vaccine storage guidelines have been written to assist all Australian immunisation service providers, including medical practices, large hospitals, clinics, mobile services and outreach providers. The guidelines describe the best approach to ensure that clients receive effective and potent vaccines; describe the ‘cold chain’ and provide advice on what should be done in the event of a cold chain breach; include resources such as charts and checklists; and apply to vaccines stored in purpose-built vaccine refrigerators.